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Intracytoplasmic Sperm Injection (ICSI) is an advanced procedure and performed as part of an IVF treatment cycle to achieve higher fertilization rates. During conventional IVF, due to various reasons sometimes the sperm is unable to penetrate through the thick outer layer of the egg and hence fertilization does not take place. ICSI involves injecting the sperm directly into the cytoplasm of the egg ensuring that fertilization takes place. ICSI is a delicate procedure and performed by experienced embryologists in a very advanced and high-tech lab . One of the advantages of ICSI technique is that it requires one sperm per egg and patients having male infertility issues. As far as patients are concerned, undergoing ICSI is just the same as conventional IVF.